Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.
Identifieur interne : 002C03 ( Main/Exploration ); précédent : 002C02; suivant : 002C04Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.
Auteurs : Lingyun Zhong [République populaire de Chine] ; Ligang Zhou ; Yaming Zhou ; Yuanquan Chen ; Peng Sui ; Jingguo Wang ; Mingan WangSource :
- Natural product research [ 1478-6427 ] ; 2012.
Descripteurs français
- KwdFr :
- Anti-infectieux (pharmacologie), Concentration inhibitrice 50 (MeSH), Flavonoïdes (composition chimique), Flavonoïdes (pharmacologie), Magnaporthe (effets des médicaments et des substances chimiques), Populus (composition chimique), Pseudomonas (effets des médicaments et des substances chimiques), Ralstonia (effets des médicaments et des substances chimiques), Relation dose-effet des médicaments (MeSH), Structure moléculaire (MeSH), Tests de sensibilité microbienne (MeSH), Xanthomonas vesicatoria (effets des médicaments et des substances chimiques), Évaluation préclinique de médicament (MeSH).
- MESH :
- composition chimique : Flavonoïdes, Populus.
- effets des médicaments et des substances chimiques : Magnaporthe, Pseudomonas, Ralstonia, Xanthomonas vesicatoria.
- pharmacologie : Anti-infectieux, Flavonoïdes.
- Concentration inhibitrice 50, Relation dose-effet des médicaments, Structure moléculaire, Tests de sensibilité microbienne, Évaluation préclinique de médicament.
English descriptors
- KwdEn :
- Anti-Infective Agents (pharmacology), Dose-Response Relationship, Drug (MeSH), Drug Evaluation, Preclinical (MeSH), Flavonoids (chemistry), Flavonoids (pharmacology), Inhibitory Concentration 50 (MeSH), Magnaporthe (drug effects), Microbial Sensitivity Tests (MeSH), Molecular Structure (MeSH), Populus (chemistry), Pseudomonas (drug effects), Ralstonia (drug effects), Xanthomonas vesicatoria (drug effects).
- MESH :
- chemical , chemistry : Flavonoids.
- chemical , pharmacology : Anti-Infective Agents, Flavonoids.
- chemistry : Populus.
- drug effects : Magnaporthe, Pseudomonas, Ralstonia, Xanthomonas vesicatoria.
- Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Inhibitory Concentration 50, Microbial Sensitivity Tests, Molecular Structure.
Abstract
A bioassay-guided fractionation of the ethyl acetate extract from the twigs of the hybrid poplar 'Neva', Populus nigra L. × Populus deltoides Marsh, led to the isolation of three flavonoids, which were identified by means of spectrometric and physicochemical analysis as 5-hydroxy-7-methoxy-flavone (1), 5,7-dihydoxy-flavone (2) and 5,7-dihydroxy-flavonol (3). These compounds were further screened for their antimicrobial activity against plant pathogens, including three bacteria (Pseudomonas lachrymans, Ralstonia solanacearum and Xanthomonas vesicatoria) and one fungus (Magnaporthe oryzae). Compounds 2 and 3 showed significant antibacterial activity, with minimum inhibitory concentrations (MICs) ranging from 15 to 25 µg mL(-1), and median inhibitory concentrations (IC(50) values) from 4 to 18 µg mL(-1). The results obtained provide promising baseline information for the potential use of the extract and flavonoids from this plant as antimicrobial agents to help control plant diseases.
DOI: 10.1080/14786411003675667
PubMed: 21416454
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.</title><author><name sortKey="Zhong, Lingyun" sort="Zhong, Lingyun" uniqKey="Zhong L" first="Lingyun" last="Zhong">Lingyun Zhong</name><affiliation wicri:level="3"><nlm:affiliation>College of Agronomy and Biotechnology, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Agronomy and Biotechnology, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Ligang" sort="Zhou, Ligang" uniqKey="Zhou L" first="Ligang" last="Zhou">Ligang Zhou</name></author><author><name sortKey="Zhou, Yaming" sort="Zhou, Yaming" uniqKey="Zhou Y" first="Yaming" last="Zhou">Yaming Zhou</name></author><author><name sortKey="Chen, Yuanquan" sort="Chen, Yuanquan" uniqKey="Chen Y" first="Yuanquan" last="Chen">Yuanquan Chen</name></author><author><name sortKey="Sui, Peng" sort="Sui, Peng" uniqKey="Sui P" first="Peng" last="Sui">Peng Sui</name></author><author><name sortKey="Wang, Jingguo" sort="Wang, Jingguo" uniqKey="Wang J" first="Jingguo" last="Wang">Jingguo Wang</name></author><author><name sortKey="Wang, Mingan" sort="Wang, Mingan" uniqKey="Wang M" first="Mingan" last="Wang">Mingan Wang</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:21416454</idno><idno type="pmid">21416454</idno><idno type="doi">10.1080/14786411003675667</idno><idno type="wicri:Area/Main/Corpus">002E82</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">002E82</idno><idno type="wicri:Area/Main/Curation">002E82</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">002E82</idno><idno type="wicri:Area/Main/Exploration">002E82</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.</title><author><name sortKey="Zhong, Lingyun" sort="Zhong, Lingyun" uniqKey="Zhong L" first="Lingyun" last="Zhong">Lingyun Zhong</name><affiliation wicri:level="3"><nlm:affiliation>College of Agronomy and Biotechnology, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Agronomy and Biotechnology, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Ligang" sort="Zhou, Ligang" uniqKey="Zhou L" first="Ligang" last="Zhou">Ligang Zhou</name></author><author><name sortKey="Zhou, Yaming" sort="Zhou, Yaming" uniqKey="Zhou Y" first="Yaming" last="Zhou">Yaming Zhou</name></author><author><name sortKey="Chen, Yuanquan" sort="Chen, Yuanquan" uniqKey="Chen Y" first="Yuanquan" last="Chen">Yuanquan Chen</name></author><author><name sortKey="Sui, Peng" sort="Sui, Peng" uniqKey="Sui P" first="Peng" last="Sui">Peng Sui</name></author><author><name sortKey="Wang, Jingguo" sort="Wang, Jingguo" uniqKey="Wang J" first="Jingguo" last="Wang">Jingguo Wang</name></author><author><name sortKey="Wang, Mingan" sort="Wang, Mingan" uniqKey="Wang M" first="Mingan" last="Wang">Mingan Wang</name></author></analytic><series><title level="j">Natural product research</title><idno type="eISSN">1478-6427</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Infective Agents (pharmacology)</term><term>Dose-Response Relationship, Drug (MeSH)</term><term>Drug Evaluation, Preclinical (MeSH)</term><term>Flavonoids (chemistry)</term><term>Flavonoids (pharmacology)</term><term>Inhibitory Concentration 50 (MeSH)</term><term>Magnaporthe (drug effects)</term><term>Microbial Sensitivity Tests (MeSH)</term><term>Molecular Structure (MeSH)</term><term>Populus (chemistry)</term><term>Pseudomonas (drug effects)</term><term>Ralstonia (drug effects)</term><term>Xanthomonas vesicatoria (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anti-infectieux (pharmacologie)</term><term>Concentration inhibitrice 50 (MeSH)</term><term>Flavonoïdes (composition chimique)</term><term>Flavonoïdes (pharmacologie)</term><term>Magnaporthe (effets des médicaments et des substances chimiques)</term><term>Populus (composition chimique)</term><term>Pseudomonas (effets des médicaments et des substances chimiques)</term><term>Ralstonia (effets des médicaments et des substances chimiques)</term><term>Relation dose-effet des médicaments (MeSH)</term><term>Structure moléculaire (MeSH)</term><term>Tests de sensibilité microbienne (MeSH)</term><term>Xanthomonas vesicatoria (effets des médicaments et des substances chimiques)</term><term>Évaluation préclinique de médicament (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Flavonoids</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Infective Agents</term><term>Flavonoids</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Populus</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Flavonoïdes</term><term>Populus</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Magnaporthe</term><term>Pseudomonas</term><term>Ralstonia</term><term>Xanthomonas vesicatoria</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Magnaporthe</term><term>Pseudomonas</term><term>Ralstonia</term><term>Xanthomonas vesicatoria</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Anti-infectieux</term><term>Flavonoïdes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Dose-Response Relationship, Drug</term><term>Drug Evaluation, Preclinical</term><term>Inhibitory Concentration 50</term><term>Microbial Sensitivity Tests</term><term>Molecular Structure</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Concentration inhibitrice 50</term><term>Relation dose-effet des médicaments</term><term>Structure moléculaire</term><term>Tests de sensibilité microbienne</term><term>Évaluation préclinique de médicament</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A bioassay-guided fractionation of the ethyl acetate extract from the twigs of the hybrid poplar 'Neva', Populus nigra L. × Populus deltoides Marsh, led to the isolation of three flavonoids, which were identified by means of spectrometric and physicochemical analysis as 5-hydroxy-7-methoxy-flavone (1), 5,7-dihydoxy-flavone (2) and 5,7-dihydroxy-flavonol (3). These compounds were further screened for their antimicrobial activity against plant pathogens, including three bacteria (Pseudomonas lachrymans, Ralstonia solanacearum and Xanthomonas vesicatoria) and one fungus (Magnaporthe oryzae). Compounds 2 and 3 showed significant antibacterial activity, with minimum inhibitory concentrations (MICs) ranging from 15 to 25 µg mL(-1), and median inhibitory concentrations (IC(50) values) from 4 to 18 µg mL(-1). The results obtained provide promising baseline information for the potential use of the extract and flavonoids from this plant as antimicrobial agents to help control plant diseases.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21416454</PMID><DateCompleted><Year>2012</Year><Month>08</Month><Day>10</Day></DateCompleted><DateRevised><Year>2012</Year><Month>09</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1478-6427</ISSN><JournalIssue CitedMedium="Internet"><Volume>26</Volume><Issue>4</Issue><PubDate><Year>2012</Year></PubDate></JournalIssue><Title>Natural product research</Title><ISOAbbreviation>Nat Prod Res</ISOAbbreviation></Journal><ArticleTitle>Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.</ArticleTitle><Pagination><MedlinePgn>307-13</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1080/14786411003675667</ELocationID><Abstract><AbstractText>A bioassay-guided fractionation of the ethyl acetate extract from the twigs of the hybrid poplar 'Neva', Populus nigra L. × Populus deltoides Marsh, led to the isolation of three flavonoids, which were identified by means of spectrometric and physicochemical analysis as 5-hydroxy-7-methoxy-flavone (1), 5,7-dihydoxy-flavone (2) and 5,7-dihydroxy-flavonol (3). These compounds were further screened for their antimicrobial activity against plant pathogens, including three bacteria (Pseudomonas lachrymans, Ralstonia solanacearum and Xanthomonas vesicatoria) and one fungus (Magnaporthe oryzae). Compounds 2 and 3 showed significant antibacterial activity, with minimum inhibitory concentrations (MICs) ranging from 15 to 25 µg mL(-1), and median inhibitory concentrations (IC(50) values) from 4 to 18 µg mL(-1). The results obtained provide promising baseline information for the potential use of the extract and flavonoids from this plant as antimicrobial agents to help control plant diseases.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhong</LastName><ForeName>Lingyun</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>College of Agronomy and Biotechnology, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Ligang</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Yaming</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Yuanquan</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Sui</LastName><ForeName>Peng</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Jingguo</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Mingan</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>06</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Nat Prod Res</MedlineTA><NlmUniqueID>101167924</NlmUniqueID><ISSNLinking>1478-6419</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C574172">5,7-dihydoxyflavone</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C574173">5,7-dihydroxyflavonol</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000890">Anti-Infective Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005419">Flavonoids</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000890" MajorTopicYN="N">Anti-Infective Agents</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004305" MajorTopicYN="N">Dose-Response Relationship, Drug</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004353" MajorTopicYN="N">Drug Evaluation, Preclinical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005419" MajorTopicYN="N">Flavonoids</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020128" MajorTopicYN="N">Inhibitory Concentration 50</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020082" MajorTopicYN="N">Magnaporthe</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015394" MajorTopicYN="N">Molecular Structure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011549" MajorTopicYN="N">Pseudomonas</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D043367" MajorTopicYN="N">Ralstonia</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D044184" MajorTopicYN="N">Xanthomonas vesicatoria</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>8</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">21416454</ArticleId><ArticleId IdType="pii">935037555</ArticleId><ArticleId IdType="doi">10.1080/14786411003675667</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Chen, Yuanquan" sort="Chen, Yuanquan" uniqKey="Chen Y" first="Yuanquan" last="Chen">Yuanquan Chen</name><name sortKey="Sui, Peng" sort="Sui, Peng" uniqKey="Sui P" first="Peng" last="Sui">Peng Sui</name><name sortKey="Wang, Jingguo" sort="Wang, Jingguo" uniqKey="Wang J" first="Jingguo" last="Wang">Jingguo Wang</name><name sortKey="Wang, Mingan" sort="Wang, Mingan" uniqKey="Wang M" first="Mingan" last="Wang">Mingan Wang</name><name sortKey="Zhou, Ligang" sort="Zhou, Ligang" uniqKey="Zhou L" first="Ligang" last="Zhou">Ligang Zhou</name><name sortKey="Zhou, Yaming" sort="Zhou, Yaming" uniqKey="Zhou Y" first="Yaming" last="Zhou">Yaming Zhou</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Zhong, Lingyun" sort="Zhong, Lingyun" uniqKey="Zhong L" first="Lingyun" last="Zhong">Lingyun Zhong</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PoplarV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002C03 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002C03 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PoplarV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:21416454
|texte= Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21416454" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PoplarV1
| This area was generated with Dilib version V0.6.37. |  |